Lab's papers
Infection of the Developing Central Nervous System of Drosophila by Mammalian Eukaryotic and Prokaryotic Pathogens. Benmimoun B, Winkler B and Spéder P.
Bio Protoc. 2022 Dec 5;12(23):e4563. doi: 10.21769/BioProtoc.4563. LINK
A corset of adhesions during development establishes individual neural stem cell niches and controls adult behaviour. Banach-Latapy A, Rincheval V, Briand D, Guénal I, Spéder P.
bioRxiv
doi: https://doi.org/10.1101/2022.10.04.510893
An interplay between cellular growth and atypical fusion defines morphogenesis of a modular glial niche in Drosophila. Rujano MA, Briand D, Ðelić B, Marc J, Spéder P.
Nat Commun. 2022 Aug 25;13(1):4999. doi: 10.1038/s41467-022-32685-3. LINK
Brain inflammation triggers macrophage invasion across the blood-brain barrier in Drosophila during pupal stages
Bente Winkler, Dominik Funke, Billel Benmimoun, Pauline Spéder, Simone Rey, Mary A Logan, Christian Klämbt
Sci Adv. 2021 Oct 29;7(44):eabh0050. doi: 10.1126/sciadv.abh0050. Epub 2021 Oct 27. LINK
Breaking down barriers: Tumors make a leaky brain. [PREVIEW]
Billel Benmimoun and Pauline Spéder
Dev Cell. 2021 Oct 11;56(19):2683-2685. doi: 10.1016/j.devcel.2021.09.018. LINK
An original infection model identifies host lipoprotein import as a route for blood-brain barrier crossing
Billel Benmimoun, Florentia Papastefanaki, Bruno Périchon, Katerina Segklia, Nicolas Roby, Vivi Miriagou, Christine Schmitt, Shaynoor Dramsi, Rebecca Matsas, Pauline Spéder
Nat Commun. 2020 Nov 30;11(1):6106. doi: 10.1038/s41467-020-19826-2. LINK
Pauline's papers
Research papers
Molecular to organismal chirality is induced by the conserved Myosin ID.
Lebreton G, Géminard C, Lapraz F, Pyrpassopoulos S, Cerezo D, Spéder P, Ostap EM, Noselli S. Science. 2018 Nov 23;362(6417):949-952. LINK
Systemic and local cues drive neural stem cell niche remodeling during neurogenesis in Drosophila.
Spéder P, Brand AH. eLife. 2018 Jan 4;7. LINK
Gap junction proteins in the blood-brain barrier control nutrient-dependent reactivation of Drosophila neural stem cells. Spéder P, Brand AH. Dev Cell. 2014 Aug 11;30(3):309-21. LINK
Comments in: Closing the gap between glia and neuroblast proliferation.
Limmer S., Klämbt C. LINK
Drosophila left/right asymmetry establishment is controlled by the Hox gene abdominal-B. Coutelis JB, Géminard C, Spéder P, Suzanne M, Petzoldt AG, Noselli S. Dev Cell. 2013 Jan 14;24(1):89-97. LINK
DE-Cadherin regulates unconventional Myosin ID and Myosin IC in Drosophila left-right asymmetry establishment. Petzoldt AG, Coutelis JB, Géminard C, Spéder P, Suzanne M, Cerezo D, Noselli S. Development. 2012 May;139(10):1874-84. LINK
Coupling of apoptosis and L/R patterning controls stepwise organ looping. Suzanne M, Petzoldt AG, Spéder P, Coutelis JB, Steller H, Noselli S. Curr Biol. 2010 Oct 12;20(19):1773-8. LINK
The Drosophila serine protease homologue Scarface regulates JNK signalling in a negative-feedback loop during epithelial morphogenesis. Rousset R, Bono-Lauriol S, Gettings M, Suzanne M, Spéder P, Noselli S. Development. 2010 Jul;137(13):2177-86. LINK
Spéder P*, Adám G*, Noselli S. (2006). Type ID unconventional mysoin controls left-right asymmetry in Drosophila. Nature. 2006 Apr 6;440(7085):803-7. LINK
Hozumi S, Maeda R, Taniguchi K, Kanai M, Shirakabe S, Sasamura T, Spéder P, Noselli S, Aigaki T, Murakami R, Matsuno K. (2006). An unconventional myosin in Drosophila reverses the default handedness in visceral organs. Nature. 2006 Apr 6;440(7085):798-802. LINK
Maskell PD, Spéder P, Newberry NR, Bermùdez I. (2003). Inhibition of human alpha 7 nicotinic acetylcholine receptors by open channel blockers of N-methyl-D-aspartate receptors. Br J Pharmacol. 140:1313-9. LINK
Resource papers
Analysis of the expression patterns, sub-cellular localisations and interaction partners of Drosophila proteins using a pigP protein trap library. Lowe N1,†, Rees JS1,2,†, Roote J3,†, Ryder E3,10,†, Armean IM2,11, Johnson G3, Drummond E3, Spriggs H3, Drummond J3, Magbanua JP3, Naylor H4, Sanson B4, Bastock R1, Huelsmann S1, Trovisco V1, Landgraf M5, Knowles-Barley S6, Armstrong JD6, White-Cooper H7, Hansen C8 , Phillips R9, the UK Drosophila protein trap screening consortium*, Lilley KS2, Russell S3, St Johnston D. Development. 2014 Oct;141(20):3994-4005. LINK
* including Spéder P
Reviews
Control of brain development and homeostasis by local and systemic insulin signalling. Liu J, Spéder P, Brand AH. Diabetes Obes Metab. 2014 Sep;16 Suppl 1:16-20. LINK
Nutrient control of neural stem cells. Spéder P, Liu J, Brand AH. Curr Opin Cell Biol. 2011 Dec;23(6):724-9. LINK
Left-right asymmetry in Drosophila. Coutelis JB, Petzoldt AG, Spéder P, Suzanne M, Noselli S. Semin Cell Dev Biol. 2008 Jun;19(3):252-62. LINK
Spéder* P, Petzoldt* A, Suzanne* M, Noselli S. (2007). Strategies to establish left-right asymmetry in vertebrates and invertebrates. Curr Opin Genet Dev. 2007 Aug;17(4):351-8. LINK
Spéder P, Noselli S. (2007). Left-right asymmetry: class I myosins show the direction. Curr Opin Cell Biol. 19:82-7. LINK
Infection of the Developing Central Nervous System of Drosophila by Mammalian Eukaryotic and Prokaryotic Pathogens. Benmimoun B, Winkler B and Spéder P.
Bio Protoc. 2022 Dec 5;12(23):e4563. doi: 10.21769/BioProtoc.4563. LINK
A corset of adhesions during development establishes individual neural stem cell niches and controls adult behaviour. Banach-Latapy A, Rincheval V, Briand D, Guénal I, Spéder P.
bioRxiv
doi: https://doi.org/10.1101/2022.10.04.510893
An interplay between cellular growth and atypical fusion defines morphogenesis of a modular glial niche in Drosophila. Rujano MA, Briand D, Ðelić B, Marc J, Spéder P.
Nat Commun. 2022 Aug 25;13(1):4999. doi: 10.1038/s41467-022-32685-3. LINK
Brain inflammation triggers macrophage invasion across the blood-brain barrier in Drosophila during pupal stages
Bente Winkler, Dominik Funke, Billel Benmimoun, Pauline Spéder, Simone Rey, Mary A Logan, Christian Klämbt
Sci Adv. 2021 Oct 29;7(44):eabh0050. doi: 10.1126/sciadv.abh0050. Epub 2021 Oct 27. LINK
Breaking down barriers: Tumors make a leaky brain. [PREVIEW]
Billel Benmimoun and Pauline Spéder
Dev Cell. 2021 Oct 11;56(19):2683-2685. doi: 10.1016/j.devcel.2021.09.018. LINK
An original infection model identifies host lipoprotein import as a route for blood-brain barrier crossing
Billel Benmimoun, Florentia Papastefanaki, Bruno Périchon, Katerina Segklia, Nicolas Roby, Vivi Miriagou, Christine Schmitt, Shaynoor Dramsi, Rebecca Matsas, Pauline Spéder
Nat Commun. 2020 Nov 30;11(1):6106. doi: 10.1038/s41467-020-19826-2. LINK
Pauline's papers
Research papers
Molecular to organismal chirality is induced by the conserved Myosin ID.
Lebreton G, Géminard C, Lapraz F, Pyrpassopoulos S, Cerezo D, Spéder P, Ostap EM, Noselli S. Science. 2018 Nov 23;362(6417):949-952. LINK
Systemic and local cues drive neural stem cell niche remodeling during neurogenesis in Drosophila.
Spéder P, Brand AH. eLife. 2018 Jan 4;7. LINK
Gap junction proteins in the blood-brain barrier control nutrient-dependent reactivation of Drosophila neural stem cells. Spéder P, Brand AH. Dev Cell. 2014 Aug 11;30(3):309-21. LINK
Comments in: Closing the gap between glia and neuroblast proliferation.
Limmer S., Klämbt C. LINK
Drosophila left/right asymmetry establishment is controlled by the Hox gene abdominal-B. Coutelis JB, Géminard C, Spéder P, Suzanne M, Petzoldt AG, Noselli S. Dev Cell. 2013 Jan 14;24(1):89-97. LINK
DE-Cadherin regulates unconventional Myosin ID and Myosin IC in Drosophila left-right asymmetry establishment. Petzoldt AG, Coutelis JB, Géminard C, Spéder P, Suzanne M, Cerezo D, Noselli S. Development. 2012 May;139(10):1874-84. LINK
Coupling of apoptosis and L/R patterning controls stepwise organ looping. Suzanne M, Petzoldt AG, Spéder P, Coutelis JB, Steller H, Noselli S. Curr Biol. 2010 Oct 12;20(19):1773-8. LINK
The Drosophila serine protease homologue Scarface regulates JNK signalling in a negative-feedback loop during epithelial morphogenesis. Rousset R, Bono-Lauriol S, Gettings M, Suzanne M, Spéder P, Noselli S. Development. 2010 Jul;137(13):2177-86. LINK
Spéder P*, Adám G*, Noselli S. (2006). Type ID unconventional mysoin controls left-right asymmetry in Drosophila. Nature. 2006 Apr 6;440(7085):803-7. LINK
Hozumi S, Maeda R, Taniguchi K, Kanai M, Shirakabe S, Sasamura T, Spéder P, Noselli S, Aigaki T, Murakami R, Matsuno K. (2006). An unconventional myosin in Drosophila reverses the default handedness in visceral organs. Nature. 2006 Apr 6;440(7085):798-802. LINK
Maskell PD, Spéder P, Newberry NR, Bermùdez I. (2003). Inhibition of human alpha 7 nicotinic acetylcholine receptors by open channel blockers of N-methyl-D-aspartate receptors. Br J Pharmacol. 140:1313-9. LINK
Resource papers
Analysis of the expression patterns, sub-cellular localisations and interaction partners of Drosophila proteins using a pigP protein trap library. Lowe N1,†, Rees JS1,2,†, Roote J3,†, Ryder E3,10,†, Armean IM2,11, Johnson G3, Drummond E3, Spriggs H3, Drummond J3, Magbanua JP3, Naylor H4, Sanson B4, Bastock R1, Huelsmann S1, Trovisco V1, Landgraf M5, Knowles-Barley S6, Armstrong JD6, White-Cooper H7, Hansen C8 , Phillips R9, the UK Drosophila protein trap screening consortium*, Lilley KS2, Russell S3, St Johnston D. Development. 2014 Oct;141(20):3994-4005. LINK
* including Spéder P
Reviews
Control of brain development and homeostasis by local and systemic insulin signalling. Liu J, Spéder P, Brand AH. Diabetes Obes Metab. 2014 Sep;16 Suppl 1:16-20. LINK
Nutrient control of neural stem cells. Spéder P, Liu J, Brand AH. Curr Opin Cell Biol. 2011 Dec;23(6):724-9. LINK
Left-right asymmetry in Drosophila. Coutelis JB, Petzoldt AG, Spéder P, Suzanne M, Noselli S. Semin Cell Dev Biol. 2008 Jun;19(3):252-62. LINK
Spéder* P, Petzoldt* A, Suzanne* M, Noselli S. (2007). Strategies to establish left-right asymmetry in vertebrates and invertebrates. Curr Opin Genet Dev. 2007 Aug;17(4):351-8. LINK
Spéder P, Noselli S. (2007). Left-right asymmetry: class I myosins show the direction. Curr Opin Cell Biol. 19:82-7. LINK
